Thunberginol A
Thunberginol A is an isocoumarin found in Hydrangea macrophylla[1] and the herbal preparation hydrangeae dulcis folium which is produced from its leaves.[2][3]
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| IUPAC name
3-(3,4-dihydroxyphenyl)-8-hydroxyisochromen-1-one | |
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3D model (JSmol) |
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CompTox Dashboard (EPA) |
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| Properties | |
| C15H10O5 | |
| Molar mass | 270.240 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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References
- Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1999). "Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols a and F from Hydrangea macrophylla SERINGE var. Thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats". Biological & Pharmaceutical Bulletin. 22 (8): 870–872. doi:10.1248/bpb.22.870. PMID 10480329. INIST:1959604.
- Yamahara, J.; Matsuda, H.; Shimoda, H.; Wariishi, N.; Yagi, N.; Murakami, N.; Yoshikawa, M. (1995). "Effects of thunberginol a contained in Hydrangeae dulcis forium on types I-IV allergies". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese). 105 (5): 365–379. doi:10.1254/fpj.105.365. PMID 7628785.
- Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1998). "Immunomodulatory activity of thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens". Bioorganic & Medicinal Chemistry Letters. 8 (3): 215–20. doi:10.1016/S0960-894X(97)10221-9. PMID 9871657.
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