Trans-epoxysuccinate hydrolase
In enzymology, a trans-epoxysuccinate hydrolase (EC 3.3.2.4) is an enzyme that catalyzes the chemical reaction
- trans-2,3-epoxysuccinate + H2O meso-tartrate
| trans-epoxysuccinate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.3.2.4 | ||||||||
| CAS number | 37290-73-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are trans-2,3-epoxysuccinate and H2O, whereas its product is meso-tartrate.
This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is trans-2,3-epoxysuccinate hydrolase. Other names in common use include trans-epoxysuccinate hydratase, and tartrate epoxydase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- Allen RH, Jakoby WB (1969). "Tartaric acid metabolism. IX. Synthesis with tartrate epoxidase". J. Biol. Chem. 244 (8): 2078–84. PMID 5782001.
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