Tuberculocide

A tuberculocide is a substance or a process which disables or destroys the spore which causes tuberculosis, Mycobacterium tuberculosis.

History

In 1955, Bergsmann studied dairin as a tuberculocide.[1]

In 1976, Sachse studied peracetic acid as a tuberculocide.[2]

In 1998, Wang and Ding studied diterpenoids from the roots of Euphorbia ebracteolata (one of the Euphorbia genus) as a tuberculocide.[3]

In 2010, Zhang et al. reported that Euphorbia fischeriana had been used especially in Asia as a tuberculocide.[4]

In 2011, Nde et al. studied three oxidative disinfectants as tuberculocides.[5]

References
  1. BERGSMANN O (1955). "A report on the clinical application of dairin, a tuberculocide". Die Medizinische (29–30): 1053–5. PMID 13253229.
  2. Sachse, H. (1976). "Peracetic acid as a disinfectant in the fight against tuberculosis--experimental data-- (Author's transl)". Zeitschrift Fur Erkrankungen der Atmungsorgane. 144 (1): 33–8. PMID 823717.
  3. Wang, W.; Ding, X. (1998). "Studies on diterpenoids from the roots of Euphorbia ebracteolata". Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 33 (2): 128–31. PMID 11938948.
  4. Zhang, X.; Yao, Y.; Lou, Y.; Jiang, H.; Wang, X.; Chai, X.; Zeng, S. (2010). "Metabolism of ebracteolata compound B studied in vitro with human liver microsomes, HepG2 cells, and recombinant human enzymes". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 38 (12): 2157–65. doi:10.1124/dmd.110.034496. PMID 20837661. S2CID 19365620.
  5. Nde, C. W.; Toghrol, F.; Jang, H. J.; Bentley, W. E. (2011). "Toxicogenomic response of Mycobacterium bovis BCG to peracetic acid and a comparative analysis of the M. Bovis BCG response to three oxidative disinfectants". Applied Microbiology and Biotechnology. 90 (1): 277–304. doi:10.1007/s00253-010-2931-6. PMID 21152916. S2CID 21943292.
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