Two Blind Mice

The plot revolves around the Office of Medicinal Herbs, a fictitious U.S. government bureau abolished by Congress four years before the setting of the play. Its two elderly officials have refused to accept the closing of the office, which represents their lives' work, and they keep it running quietly. Deprived of funding by the abolition, they make ends meet by renting out the rooms and by running a parking lot on the front lawn. To avoid problems with what remains of the Government, they never answer the phone.[2]

Thurston discovers the office and sets out to aid the workers. Through an elaborate series of practical jokes, he involves the Armed Forces and the State Department, eventually winning the day for the elderly ladies. In the process, he also wins back his former wife.[2]

The opening night, March 2, 1949, saw the audience enjoy the production[2] The New York Times's critic, Brooks Atkinson, however, gave it a lukewarm review,[2] and later in March criticized the Spewacks for wasting an intriguing setup by turning it over to Thurston, whom Atkinson dubbed "an adolescent journalistic prankster who has nothing to give anybody except impudence, irresponsibility and show clichés".[3] The play closed July 16, 1949, and its two mascots, white mice, were put up for adoption.[4] In his autobiography, Douglas laid the blame for the play's failure to run more than four and a half months on Broadway on Samuel Spewack's insistence on not only writing, but also directing the play.

The show began a tour throughout the eastern half of the United States and into Canada in early 1950, after adjustments in the show insisted upon by Douglas were made, and ran throughout the year. The show kept Douglas away from California during his wife Helen Gahagan Douglas's run for United States Senate against Richard Nixon, a campaign which proved extremely nasty.