UBE1DC1

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.[5][6][7]

UBA5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesUBA5, THIFP1, UBE1DC1, ubiquitin like modifier activating enzyme 5, SCAR24, EIEE44
External IDsOMIM: 610552 MGI: 1913913 HomoloGene: 11738 GeneCards: UBA5
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q22.1Start132,654,446 bp[1]
End132,678,097 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

79876

66663

Ensembl

ENSG00000081307

ENSMUSG00000032557

UniProt

Q9GZZ9

Q8VE47

RefSeq (mRNA)

NM_024818
NM_198329
NM_001320210
NM_001321238
NM_001321239

NM_025692

RefSeq (protein)

NP_001307139
NP_001308167
NP_001308168
NP_079094
NP_938143

NP_079968

Location (UCSC)Chr 3: 132.65 – 132.68 MbChr 9: 104.05 – 104.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000081307 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032557 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, Okazaki N, Ueno T, Kominami E, Natsume T, Tanaka K (May 2004). "A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier". EMBO J. 23 (9): 1977–86. doi:10.1038/sj.emboj.7600205. PMC 404325. PMID 15071506.
  7. "Entrez Gene: UBE1DC1 ubiquitin-activating enzyme E1-domain containing 1".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q9GZZ9 (Human Ubiquitin-like modifier-activating enzyme 5 (UBE1DC1)) at the PDBe-KB.


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