Working Formulation
The Working formulation is an obsolete classification of non-Hodgkin lymphomas, first proposed in 1982.[1] It has since been replaced by other lymphoma classifications, the latest published by the WHO in 2016 [2] but is still used by cancer agencies for compilation of lymphoma statistics.
Low Grade
- Malignant lymphoma, small lymphocytic (chronic lymphocytic leukemia)
- Malignant lymphoma, follicular, predominantly small cleaved cell
- Malignant lymphoma, follicular, mixed (small cleaved and large cell)
Intermediate grade
- Malignant lymphoma, follicular, predominantly large cell
- Malignant lymphoma, diffuse, small cleaved cell
- Malignant lymphoma, diffuse, mixed small and large cell
- Malignant lymphoma, diffuse, large cell
High grade
- Malignant lymphoma, large cell, immunoblastic
- Malignant lymphoma, lymphoblastic
- Malignant lymphoma, small noncleaved cells (Burkitt lymphoma)
Miscellaneous
- Composite
- Mycosis fungoides
- Histiocytic
- Extramedullary plasmacytoma
- Unclassifiable
References
- MacKenzie RG, Rusthoven JJ (1985). "Management of localized non-Hodgkin's lymphoma". CMAJ. 133 (6): 559–64. PMC 1346220. PMID 3896450.
- https://www.iarc.fr/news-events/who-classification-of-tumours-of-haematopoietic-and-lymphoid-tissues-2/
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