Yunnanxane

Yunnanxane
Names
	Systematic IUPAC name 2,5,10-Triacetoxytaxa-4(20),11-dien-14-yl 3-hydroxy-2-methylbutanoate
Identifiers
CAS Number	139713-81-8 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL245750;
ChemSpider	4474732;
PubChem CID	11226788;
CompTox Dashboard (EPA)	DTXSID30930563 ;
	SMILES CC1(C)C([C@@H](OC(C)=O)C[C@@]2(C)[C@](C([C@@H](OC(C)=O)CC2)=C)([H])[C@@H]3OC(C)=O)=C(C)[C@@H](OC([C@H](C)[C@H](C)O)=O)C[C@]13[H];
Properties
Chemical formula	C31H46O9
Molar mass	562.700 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Yunnanxane is a bioactive taxane diterpenoid first isolated from Taxus wallichiana. Yunnanxane was later isolated from cell cultures of Taxus cuspidata and Taxus chinensis. Four homologous esters of yunnanxane have also been isolated from Taxus. Yunnanxane is reported to have anticancer activity in vitro.[1][2]

References

Chen WM, Zhang PL, Wu B, Zheng QT (1991). "[Studies on the chemical constituents of Taxus yunnanensis]". Yao Xue Xue Bao. 26 (10): 747–54. PMID 1688071.
Ma W, Stahlhut RW, Adams TL, Park GL, Evans WA, Blumenthal SG, et al. (1994). "Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei". J Nat Prod. 57 (9): 1320–4. doi:10.1021/np50111a027. PMID 7798969.

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[pmid1688071-1] Chen WM, Zhang PL, Wu B, Zheng QT (1991). "[Studies on the chemical constituents of Taxus yunnanensis]". Yao Xue Xue Bao. 26 (10): 747–54. PMID 1688071.

[pmid7798969-2] Ma W, Stahlhut RW, Adams TL, Park GL, Evans WA, Blumenthal SG, et al. (1994). "Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei". J Nat Prod. 57 (9): 1320–4. doi:10.1021/np50111a027. PMID 7798969.

Yunnanxane

See also

References