1945 World Series

The visiting Cubs began with a bang, scoring four times in the first. With two outs and runners on first and third, a passed ball by future Hall of Famer Hal Newhouser scored the game's first run. After an intentional walk, a two-run Bill Nicholson double and Mickey Livingston's RBI single made it 4–0 Cubs. In the third, after a leadoff double, Phil Cavarretta's single and Andy Pafko's double scored a run each. One out later, Livingston's second RBI single of the game knocked Newhouser out of the game. Cavarretta's two-out home run in the seventh off Jim Tobin made it 8–0. Pafko then singled, stole second, moved to third on a passed ball, and scored the game's last run on Nicholson's single. Hank Borowy pitched a complete game shutout despite allowing 12 base runners as the Cubs took a 1–0 series lead.

The Cubs struck first when Phil Cavarretta doubled with one out in the fourth and scored on Bill Nicholson's single. After 13 innings without a run, Detroit finally got going in a big way in the fifth. Hank Wyse got two outs, before allowing a single and walk. Doc Cramer's RBI single tied the game before Hank Greenberg's three-run home run put the Tigers up 4–1 Virgil Trucks allowed no other runs in a complete game as the Tigers tied the series at a game apiece.

Claude Passeau pitched a complete game one-hitter. The only hit of the game came with two outs in the second inning off the bat of Rudy York. Other Series pitchers in the "low-hit Complete Game Club" are:

The Cubs scored two runs in the fourth off Stubby Overmire on RBI singles by Bill Nicholson and Roy Hughes after a leadoff double and one-out walk. They added another run in the seventh off Al Benton when Mickey Livingston hit a leadoff double, moved to third on a groundout and scored on Claude Passeau's sacrifice fly. They now led the series 2–1.

The Series shifted to Wrigley Field and the so-called Curse of the Billy Goat began. Dizzy Trout went the distance for Detroit with a five-hitter. A four-run fourth against Cub starter Ray Prim gave Trout all the runs he needed. After a one-out walk and single, Hank Greenberg's RBI single and Roy Cullenbine's RBI double knocked starter Ray Prim out of the game. Paul Derringer intentionally walked Rudy York before Jimmy Outlaw's groundout and Paul Richards's single scored a run each. The Cubs scored their only run of the game in the sixth when Don Johnson hit a leadoff triple and scored on Peanuts Lowrey's groundout. The series was now tied 2–2.

Back in form, Hal Newhouser went the distance for Detroit, striking out nine. The Tigers struck first in the top of the third on Doc Cramer's sacrifice fly with runners on first and third, but the Cubs tied the game in the bottom half when Hank Borowy doubled with two outs and scored on Stan Hack's single. In the sixth, Cramer hit a leadoff single and scored on Hank Greenberg's double. After a single, Rudy York's RBI single knocked starter Hank Borowy out of the game. Hy Vandenberg in relief intentionally walked Paul Richards with one out to load the bases before a walk to Newhouser and Skeeter Webb's groundout scored a run each. Next inning, Jimmy Outlaw's sacrifice fly with runners on first and third off Paul Derringer made it 6–1 Tigers. In the bottom of the inning, with runners on first and third with two outs, Bill Nicholson's fielder's choice and Mickey Livingston's ground-rule double scored a run each. In the ninth, after a hit-by-pitch and double, Roy Cullenbine's two-run double off Paul Erickson made it 8–3 Tigers. In the bottom half, Phil Cavarretta hit a leadoff double and scored on Nicholson's one out single before Newhouser retired the next two batters to end the game and put the Tigers one win away from the championship.

In Game 6, the Tigers struck first on a bases-loaded walk to Paul Richards by Claude Passeau in the second. In the fifth with the bases loaded off Virgil Trucks, Stan Hack's two-run single put the Cubs up 2–1. After another walk loaded the bases, Phil Cavarretta's two-run single knocked Trucks out of the game. Back-to-back leadoff doubles next inning by Mickey Livingston and Roy Hughes off Tommy Bridges made it 5–1 Cubs. In the top of the seventh with two on and two outs, RBI singles by Roy Cullenbine off Passeau and Rudy York off Hank Wyse cut the Cubs' lead to 5–3, but they got those runs back in the bottom half on a bases loaded walk to Livingston by Bridges followed by Roy Hughes's RBI single off Al Benton. In the top of the eighth, after a leadoff walk and double, an error on Joe Hoover's ground ball scored a run, then Eddie Mayo's RBI single scored another with Hoover going to third and Mayo being tagged out at second. Ray Prim relieved Wyse and allowed a sacrifice fly to Doc Cramer before Hank Greenburg's home run tied the game. In the 12th, after a one-out single by Frank Secory off Dizzy Trout, pinch-runner Bill Schuster came all the way around on Stan Hack's walk-off double to left, forcing a Game 7.

Besides being the last World Series game the Cubs won until 2016, this would also be the second—and last—World Series game that the Cubs would win before their hometown fans at Wrigley Field, until 2016. The only other Wrigley victory was Game 5 in 1935.

The Cubs went with the overworked Borowy, who lasted just three batters, each of whom singled, the last of which scoring a run. Paul Derringer replaced him, intentionally walked Roy Cullenbine with one out to load the bases, then one out later, walked Jimmy Outlaw before Paul Richards cleared the bases with a three-run double. The Cubs got a run in the bottom of the first on Phil Cavarretta's RBI single with two on off Hal Newhouser, but in the second, Derringer allowed a two-out single, then three consecutive walks to force in another run. The Cubs got another run in the fourth when Cavaretta singled and scored on Andy Pafko's triple. In the seventh, Cullenbine drew a leadoff walk off Paul Erickson and scored on Paul Richards's two-out double. Next inning, Skeeter Webb drew a leadoff walk off Claude Passeau and scored on Eddie Mayo's double. After moving to third on a groundout, he scored on Hank Greenberg's sacrifice fly. The Cubs scored just one more run in the bottom of the inning on Bill Richardson's RBI double with two on as Newhouser pitched a complete game to give the Tigers the championship.

The Tigers would not make another World Series appearance until 1968, while the Cubs would not do so until 2016.