2016 Oklahoma vs. Texas Tech football game

The Sooners received the opening kickoff, starting at their own 25-yard line. On the first play from scrimmage, Joe Mixon was tackled for a loss of 1-yard. Oklahoma quickly set the tempo for the game, going downfield in just over a minute and a half to score the first touchdown of the game with a 56-yard pass to Mixon from Baker Mayfield; Austin Seibert missed the extra point to make the score 6–0. Following the Oklahoma touchdown, Texas Tech's offense started at their own 22-yard line, but a penalty against Oklahoma moved the Red Raiders up 5 yards. The drive was short, with Jonathan Giles fumbling the ball near midfield and was recovered by Jordan Evans for the Sooners. Following the fumble, Oklahoma scored quickly in just 3 plays in under a minute to extend the lead to 13–0. The Red Raiders got their first touchdown on the next drive with a 4-yard run from Da'Leon Ward; following Clayton Hatfield's extra point, Texas Tech trailed 7–13. Oklahoma failed to score on the next drive, one of the few drives in the game to not end in a score, having to punt the ball away. The Red Raiders made it to Oklahoma's 20-yard line, but had to settle for a 37-yard field goal from Hatfield. Oklahoma's offense went three-and-out on their next drive, with the quarter ending before they punted the ball. At the end of the first quarter, Oklahoma had a 13–10 lead over Texas Tech.

The second quarter started with Oklahoma punting the ball. Texas Tech in turn would punt on its next possession, only gaining 1-yard on the drive. On the Sooners' first play they were penalized for an ineligible receiver down field, moving back to the Texas Tech 46-yard line. On the following play, Joe Mixon would run 46 yards for a touchdown to extend the lead to 20–10. The Red Raiders' next drive would be the longest drive of the game for either team in both number of plays and time of possession; the drive lasted for 14 plays and 4:25, ending with a 11-yard touchdown run from Patrick Mahomes. Oklahoma would respond with a 23-yard field goal from Seibert on its next drive to lead 23–17. On the next drive, the Red Raiders made it to the Oklahoma 20-yard line, but a Mahomes pass was intercepted near the end zone by Steven Parker; the Sooners would fail to score off the turnover, turning the ball over on downs at the Texas Tech 20-yard line. Texas Tech would quickly march down field in under 1:30 with Mahomes throwing a 23-yard pass to Jonathan Giles for a touchdown to tie the game 23–23. Hatfield would make the point after attempt to give the Red Raiders a 24–23 lead, their first and only lead of the game. Texas Tech would only briefly hold the lead, with Oklahoma scoring in just 20 seconds with a 23-yard touchdown pass from Mayfield to Nick Basquine with 17 seconds left in the quarter. After receiving the kickoff, the Red Raiders took a knee to end the half, trailing the Sooners 24–30.

Texas Tech received the opening kickoff for the 2nd half, but went three-and-out and had to punt; this would be the last drive of the game to not end in a score until the end of the game. The Sooners would score 3 touchdowns in the quarter, all of which were passes that went for over 20 yards, while the Red Raiders scored 2, both that were passes that went over 30 yards. Oklahoma lead 51–38 at the end of the quarter, with Texas Tech in possession of the ball at the Sooners' 48-yard line.

Each team would score 2 touchdowns in the quarter, with Texas Tech scoring first with a 22-yard run from Mahomes. Oklahoma would respond on the next drive with a 15-yard pass from Mayfield to Mixon and would convert a two-point conversion with a pass from Mayfield to Westbrook. The Red Raiders would respond in just 5 plays, with a 56-yard pass from Mahomes to Keke Coutee. The next drive ended with a 42-yard touchdown run from Mixon to extend Oklahoma's lead to 66–52. On the ensuing kickoff, Reginald Davis III would return Seibert's kick to the Texas Tech 15-yard line, but a holding penalty pushed the Red Raiders back to their own 8-yard line. Texas Tech would go down field in just under 3 and a half minutes with a 3-yard pass from Mahomes to Cameron Batson with 1:38 left in the game. Trailing 59–66 with just over a minute and a half left in the game, Michael Barden attempted an onside kick for Texas Tech, but it was recovered by Oklahoma. The Sooners would run out the clock to win 66–59.