Agaritine gamma-glutamyltransferase

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agaritine gamma-glutamyltransferase
Identifiers
EC number	2.3.2.9
CAS number	37257-25-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
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NCBI	proteins

In enzymology, an agaritine gamma-glutamyltransferase (EC 2.3.2.9) is an enzyme that catalyzes the chemical reaction

agaritine + acceptor

\rightleftharpoons

4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor

Thus, the two substrates of this enzyme are agaritine and acceptor, whereas its two products are 4-hydroxymethylphenylhydrazine and gamma-L-glutamyl-acceptor.

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is (gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:acceptor gamma-glutamyltransferase. Other names in common use include (gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor), gamma-glutamyltransferase, (gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor), gamma-glutamyltransferase, (gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:acceptor, and gamma-glutamyltransferase.

References

GIGLIOTTI HJ, LEVENBERG B (1964). "STUDIES ON THE GAMMA-GLUTAMYLTRANSFERASE OF AGARICUS BISPORUS". J. Biol. Chem. 239: 2274–84. PMID 14209959.

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Transferases: acyltransferases (EC 2.3)
2.3.1: other than amino-acyl groups	acetyltransferases: Acetyl-Coenzyme A acetyltransferase N-Acetylglutamate synthase Choline acetyltransferase Dihydrolipoyl transacetylase Acetyl-CoA C-acyltransferase Beta-galactoside transacetylase Chloramphenicol acetyltransferase N-acetyltransferase Serotonin N-acetyl transferase HGSNAT ARD1A Histone acetyltransferase P300/CBP NAT2 palmitoyltransferases: Carnitine O-palmitoyltransferase CPT1 CPT2 Serine C-palmitoyltransferase SPTLC1 SPTLC2 other: Acyltransferase like 2 Aminolevulinic acid synthase Beta-ketoacyl-ACP synthase Glyceronephosphate O-acyltransferase Lecithin—cholesterol acyltransferase Glycerol-3-phosphate O-acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 2-acylglycerol-3-phosphate O-acyltransferase ABHD5
2.3.2: Aminoacyltransferases	Gamma-glutamyl transpeptidase Peptidyl transferase Transglutaminase Tissue transglutaminase Keratinocyte transglutaminase Factor XIII
2.3.3: converted into alkyl on transfer	Citrate synthase Decylcitrate synthase Citrate (Re)-synthase Decylhomocitrate synthase 2-methylcitrate synthase 2-ethylmalate synthase 3-ethylmalate synthase ATP citrate lyase Malate synthase HMG-CoA synthase HMGCS2 2-hydroxyglutarate synthase 3-propylmalate synthase 2-isopropylmalate synthase Homocitrate synthase Sulfoacetaldehyde acetyltransferase

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)