Amurensin K

Amurensin K is an oligostilbene. It is a resveratrol tetramer found in Vitis amurensis.[1] Preliminary tests have shown it to be an effective neuraminidase inhibitor against the influenza A virus subtype H1N1.[2]

Amurensin K
Names
IUPAC name
(1S,6R,7S,11bS)-6-{5-[(7S,8S)-8-(3,5-Dihydroxyphenyl)-4-hydroxy-7-(4-hydroxyphenyl)-7,8-dihydrofuro[3,2-e][1]benzofuran-2-yl]-2-hydroxyphenyl}-1,7-bis(4-hydroxyphenyl)-1,6,7,11b-tetrahydro-2-oxadibenz o[cd,h]azulene-4,8,10-triol
Identifiers
3D model (JSmol)
ChemSpider
Properties
C56H40O13
Molar mass 920.91 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Huang, Kai-Sheng; Lin, Mao; Cheng, Gui-Fang (September 2001). "Anti-inflammatory tetramers of resveratrol from the roots of Vitis amurensis and the conformations of the seven-membered ring in some oligostilbenes". Phytochemistry. 58 (2): 357–362. doi:10.1016/S0031-9422(01)00224-2. PMID 11551564.
  2. Nguyen, Thi Ngoc Anh; Dao, Trong Tuan; Tung, Bui Thanh; Choi, Hwanwon; Kim, Eunhee; Park, Junsoo; Lim, Seong-IL; Oh, Won Keun (2011). "Influenza A (H1N1) neuraminidase inhibitors from Vitis amurensis". Food Chemistry. 124 (2): 437–443. doi:10.1016/j.foodchem.2010.06.049. ISSN 0308-8146.


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