Ashwani Kumar (scientist)
Ashwani Kumar is an Indian bacteriologist, biotechnologies, and the principal scientist at the Institute of Microbial Technology (ImTech). He is known for his studies on Mycobacterium tuberculosis, the causative agent of tuberculosis. His laboratory focuses on understanding the reasons for drug tolerance observed in humans. His laboratory hypothesise that tuberculosis is a biofilm infection and that is why its treatment needs administration of multiple drugs for at least six months. The Department of Science and Technology has awarded him Swarnajayanti Fellowship for years 2016-2017.
Ashwani Kumar | |
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Born | New Delhi, India |
Nationality | Indian |
Known for | Studies on Mycobacterium tuberculosis |
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Scientific career | |
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Institutions | |
Doctoral advisor | Vani Brahmachari |
Biography
Ashwani Kumar is a principal scientist at the Institute of Microbial Technology (ImTech)[1] where he heads a laboratory, popularly known as Ashwani Kumar's Lab.[2] and serves as a principal investigator.[3] He is known to have done extensive research on Mycobacterium tuberculosis and has served as a member of MDRIpred project,[4] an open source server for predicting inhibitors against drug-tolerant M.tb H37Rv.[5] He has published a number of articles;[6] [note 1] ResearchGate, an online repository of scientific articles has listed 31 of them.[7] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for him contributions to biosciences, in 2017–18.[8]
Selected bibliography
Articles
- Kumar, Ashwani (2016-06-23). "House of cellulose – a new hideout for drug tolerant Mycobacterium tuberculosis". Microbial Cell. 3 (7): 299–301. doi:10.15698/mic2016.07.515. ISSN 2311-2638. PMC 5354596. PMID 28357368.
- Kumar, Ashwani; Bhatt, Deepak; Mavi, Parminder Singh; Trivedi, Abhishek (2016-04-25). "Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis". Nature Communications. 7: 11392. Bibcode:2016NatCo...711392T. doi:10.1038/ncomms11392. ISSN 2041-1723. PMC 4848537. PMID 27109928.
- Nisha Singh, Pallavi Kansal, Zeeshan Ahmad, Navin Baid, Hariom Kushwaha, Neeraj Khatri, Ashwani Kumar. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis. Autophagy. 2018. doi: 10.1080/15548627.2018.1436936.
- Singh, Nisha; Vats, Asheema; Sharma, Aditi; Arora, Amit; Kumar, Ashwani (2017-06-21). "The development of lower respiratory tract microbiome in mice". Microbiome. 5 (1): 61. doi:10.1186/s40168-017-0277-3. ISSN 2049-2618. PMC 5479047. PMID 28637485.
- Nupur, L. N. U.; Vats, Asheema; Dhanda, Sandeep Kumar; Raghava, Gajendra P. S.; Pinnaka, Anil Kumar; Kumar, Ashwani (2016-05-26). "ProCarDB: a database of bacterial carotenoids". BMC Microbiology. 16 (1): 96. doi:10.1186/s12866-016-0715-6. ISSN 1471-2180. PMC 4882832. PMID 27230105.
- Sarkar, Dibyendu; Kumar, Ashwani; Sevalkar, Ritesh Rajesh; Singh, Nisha; Bansal, Roohi; Goyal, Rajni; Kumar, Vijjamarri Anil (2016-09-02). "EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP". Journal of Biological Chemistry. 291 (36): 19018–19030. doi:10.1074/jbc.M116.746289. ISSN 1083-351X. PMC 5009273. PMID 27445330.
See also
Notes
- Please see Selected bibliography section
References
- "Ashwani Kumar - ImTech profile". Institute of Microbial Technology. 2019-01-14. Retrieved 2019-01-14.
- "Ashwani Kumar's lab - Institute of Microbial Technology (IMTECH)". ResearchGate. 2019-01-14. Retrieved 2019-01-14.
- "Addgene: Ashwani Kumar Lab Plasmids". www.addgene.org. 2019-01-14. Retrieved 2019-01-14.
- "MDRIpred: A webserver for predicting inhibitors against drug resistant M.Tuberculosis". crdd.osdd.net. 2019-01-14. Retrieved 2019-01-14.
- "Welcome to MDRIpred". crdd.osdd.net. 2019-01-14. Retrieved 2019-01-14.
- "Ashwani Kumar - Google Scholar Citations". scholar.google.com. 2019-01-14. Retrieved 2019-01-14.
- "Ashwani Kumar Institute of Microbial Technology - IMTECH · Molecular Mycobacteriology 28 36 ·". ResearchGate. 2019-01-14. Retrieved 2019-01-14.
- "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2019. Retrieved 2017-11-20.
External links
- "Imtech boosts kids' chemistry with science - Times of India". The Times of India. June 2, 2015. Retrieved 2019-01-14.
- "Addgene: Institute of Microbial Technology (CSIR-IMTECH)". www.addgene.org. 2019-01-14. Retrieved 2019-01-14.
- "Understanding the nature of extracellular polymeric substances of the Mycobacterium tuberculosis biofilms" (PDF). National Centre for Cell Science. 2019-01-14. Retrieved 2019-01-14.