D-arabinose 1-dehydrogenase
In enzymology, a D-arabinose 1-dehydrogenase (EC 1.1.1.116) is an enzyme that catalyzes the chemical reaction
- D-arabinose + NAD+ D-arabinono-1,4-lactone + NADH + H+
| D-arabinose 1-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.116 | ||||||||
| CAS number | 37250-47-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are D-arabinose and NAD+, whereas its 3 products are D-arabinono-1,4-lactone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinose:NAD+ 1-oxidoreductase. Other names in common use include NAD+-pentose-dehydrogenase, and arabinose(fucose)dehydrogenase.
References
- Palleroni NJ; Doudoroff M (1957). "Metabolism of carbohydrates by Pseudomonas saccharophilla. III Oxidation of D-arabinose". J. Bacteriol. 74 (2): 180–185. PMC 289912. PMID 13475218.
- Schiwara HW, Domschke W, Domagk GF (1968). "Über die Zucker-Dehydrogenasen in der Säugetierleber, I. Differenzierung verschiedener Zucker-Dehydrogenasen in der Schweineleber durch Disk-Elektrophorese und Ionenaustauschchromatographie" [Sugar dehydrogenases in mammalian liver. I. Differentiation of various sugar dehydrogenases from pig liver by disc electrophoresis and ion exchange chromatography]. Hoppe-Seyler's Z. Physiol. Chem. (in German). 349 (11): 1575–81. doi:10.1515/bchm2.1968.349.2.1575. PMID 4393642.
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