dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)
DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) (EC 1.1.1.339, tll (gene name)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose:NAD+ 4-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- dTDP-6-deoxy-beta-L-talose + NAD+ dTDP-4-dehydro-6-deoxy-beta-L-mannose + NADH + H+
| DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.339 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme from bacterium Aggregatibacter actinomycetemcomitans participates in the biosynthesis of the serotype c-specific polysaccharide antigen.
References
- Nakano Y, Suzuki N, Yoshida Y, Nezu T, Yamashita Y, Koga T (March 2000). "Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans". The Journal of Biological Chemistry. 275 (10): 6806–12. doi:10.1074/jbc.275.10.6806. PMID 10702238.
External links
- DTDP-6-deoxy-L-talose+4-dehydrogenase+(NAD+) at the US National Library of Medicine Medical Subject Headings (MeSH)
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