Discadenine synthase
In enzymology, a discadenine synthase (EC 2.5.1.24) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + N6-(Delta2-isopentenyl)-adenine 5'-methylthioadenosine + discadenine
| discadenine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.24 | ||||||||
| CAS number | 74082-52-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and N6-(Delta2-isopentenyl)-adenine, whereas its two products are 5'-methylthioadenosine and discadenine.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase. Other names in common use include discadenine synthetase, S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine, and 3-(3-amino-3-carboxypropyl)-transferase.
References
- Taya Y, Tanaka Y, Nishimura S (1978). "Cell-free biosynthesis of discadenine, a spore germination inhibitor of Dictyostelium discoideum". FEBS Lett. 89 (2): 326–8. doi:10.1016/0014-5793(78)80247-6. PMID 566219.
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