Ecdysone O-acyltransferase

In enzymology, an ecdysone O-acyltransferase (EC 2.3.1.139) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + ecdysone CoA + ecdysone palmitate
ecdysone O-acyltransferase
Identifiers
EC number2.3.1.139
CAS number120038-26-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are palmitoyl-CoA and ecdysone, whereas its two products are CoA and ecdysone palmitate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:ecdysone palmitoyltransferase. Other names in common use include acyl-CoA:ecdysone acyltransferase, and fatty acyl-CoA:ecdysone acyltransferase.

References

    • Slinger AJ, Isaac RE (1988). "Acyl-CoA-ecdysone acyltransferase activity from the ovary of P americana". Insect Biochem. 18 (8): 779–784. doi:10.1016/0020-1790(88)90100-X.


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