Ecdysone oxidase
In enzymology, an ecdysone oxidase (EC 1.1.3.16) is an enzyme that catalyzes the chemical reaction
- ecdysone + O2 3-dehydroecdysone + H2O2
| ecdysone oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.3.16 | ||||||||
| CAS number | 56803-12-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are ecdysone and O2, whereas its two products are 3-dehydroecdysone and H2O2.
This enzyme may or may not belong to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is ecdysone:oxygen 3-oxidoreductase. This enzyme might also called beta-ecdysone oxidase.
References
- Koolman J, Karlson P (1975). "Ecdysone Oxidase, an enzyme from the blowfly Calliphora erythrocephala (Meigen)". Hoppe-Seyler's Z. Physiol. Chem. 356 (7): 1131–8. doi:10.1515/bchm2.1975.356.2.1131. PMID 297.
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