Farnesol dehydrogenase
In enzymology, a farnesol dehydrogenase (EC 1.1.1.216) is an enzyme that catalyzes the chemical reaction
- 2-trans,6-trans-farnesol + NADP+ 2-trans,6-trans-farnesal + NADPH + H+
| farnesol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.216 | ||||||||
| CAS number | 90804-55-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 2-trans,6-trans-farnesol and NADP+, whereas its 3 products are 2-trans,6-trans-farnesal, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase. Other names in common use include NADP+-farnesol dehydrogenase, and farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase.
References
- Inoue H, Tsuji H, Uritani I (1984). "Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato". Agric. Biol. Chem. 48 (3): 733–738. doi:10.1271/bbb1961.48.733.
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