Ferlavirus

Ferlavirus is a genus of viruses in the family Paramyxoviridae, order Mononegavirales.[2][3] Reptiles serve as natural hosts. There is currently only one species in this genus (Reptilian ferlavirus) to accommodate a single virus, Fer-de-Lance virus (FDLV).[4]

Reptilian ferlavirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Monjiviricetes
Order: Mononegavirales
Family: Paramyxoviridae
Subfamily: Orthoparamyxovirinae
Genus: Ferlavirus
Species:
Reptilian ferlavirus
Synonyms[1]

Fer-de-Lance paramyxovirus

Structure

Ferlaviruses produce virions that are enveloped, with spherical geometries. The virion diameter is around 150 nm. Ferlavirus are linear and around 15 kb in length. The genome codes for 8 proteins.[5]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
FerlavirusSphericalEnvelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding. Reptiles serve as the natural host.[5]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
FerlavirusUnknownNoneGlycoproteinBuddingCytoplasmCytoplasmUnknown

References
  1. Rima, Bertus K.; et al. (18 July 2016). "Implementation of taxon-wide non-Latinized binomial species names in the family Paramyxoviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 28 August 2019.
  2. Rima, B; Balkema-Buschmann, A; Dundon, WG; Duprex, P; Easton, A; Fouchier, R; Kurath, G; Lamb, R; Lee, B; Rota, P; Wang, L; ICTV Report Consortium (December 2019). "ICTV Virus Taxonomy Profile: Paramyxoviridae". The Journal of General Virology. 100 (12): 1593–1594. doi:10.1099/jgv.0.001328. PMID 31609197.
  3. "ICTV Report Paramyxoviridae".
  4. Amarasinghe, Gaya K.; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Beer, Martin; Bejerman, Nicolás; Blasdell, Kim R.; Bochnowski, Alisa; Briese, Thomas (7 April 2017). "Taxonomy of the order Mononegavirales: update 2017". Archives of Virology. 162 (8): 2493–2504. doi:10.1007/s00705-017-3311-7. ISSN 1432-8798. PMC 5831667. PMID 28389807.
  5. "Viral Zone". ExPASy. Retrieved 13 August 2015.
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