Genotype–phenotype map

The genotype–phenotype map is a conceptual model in genetic architecture. Coined in a 1991 paper by Pere Alberch,[1] it models the interdependency of genotype (an organism's full hereditary information) with phenotype (an organism's actual observed properties).

A very simple genotype-phenotype map that only shows additive pleiotropy effects.

Application

The map visualises a relationship between genotype & phenotype which, crucially:[2]

  1. is of greater complexity than a straightforward one-to-one mapping of genotype to/from phenotype.
  2. accommodates a parameter space, along which at different points a given phenotype is said to be more or less stable.
  3. accommodates transformational boundaries in the parameter space, which divide phenotype states from one another.
  4. accounts for different polymorphism and/or polyphenism in populations, depending on their area of parameter space they occupy.

References
  1. Alberch, Pere. "From genes to phenotype: dynamical systems and evolvability". Retrieved 18 October 2020.
  2. Pigliucci, Massimo. "Genotype–phenotype mapping and the end of the 'genes as blueprint' metaphor". Retrieved 18 October 2020.
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