Hydroxymalonate dehydrogenase
In enzymology, a hydroxymalonate dehydrogenase (EC 1.1.1.167) is an enzyme that catalyzes the chemical reaction
- hydroxymalonate + NAD+ oxomalonate + NADH + H+
| hydroxymalonate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.167 | ||||||||
| CAS number | 58693-60-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are hydroxymalonate and NAD+, whereas its 3 products are oxomalonate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydroxymalonate:NAD+ oxidoreductase.
References
- Jukova NI, Klunova SM, Philippovich YB (1971). Biochemistry of Insects. Moscow: V.I. Lenin State Pedagogical Institute (17): 56. Missing or empty
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