Indanol dehydrogenase
In enzymology, an indanol dehydrogenase (EC 1.1.1.112) is an enzyme that catalyzes the chemical reaction
- indan-1-ol + NAD(P)+ indanone + NAD(P)H + H+
| indanol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.112 | ||||||||
| CAS number | 37250-43-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are indan-1-ol, NAD+, and NADP+, whereas its 4 products are indanone, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is indan-1-ol:NAD(P)+ 1-oxidoreductase.
References
- Billings RE, Sullivan HR, McMahon RE (1971). "The dehydrogenation of 1-indanol by a soluble oxidoreductase from bovine liver". J. Biol. Chem. 246 (11): 3512–7. PMID 4397102.
- Hara A, Nakagawa M, Taniguchi H, Sawada H (November 1989). "3(20)α-Hydroxysteroid Dehydrogenase Activity of Monkey Liver Indanol Dehydrogenase". J. Biochem. Tokyo. 106 (5): 900–3. PMID 2559080.
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