Isopiperitenol dehydrogenase
In enzymology, an isopiperitenol dehydrogenase (EC 1.1.1.223) is an enzyme that catalyzes the chemical reaction
- (-)-trans-isopiperitenol + NAD+ (-)-isopiperitenone + NADH + H+
isopiperitenol dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.223 | ||||||||
CAS number | 96595-05-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are (-)-trans-isopiperitenol and NAD+, whereas its 3 products are (-)-isopiperitenone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (-)-trans-isopiperitenol:NAD+ oxidoreductase. This enzyme participates in monoterpenoid biosynthesis.
References
- Kjonaas RB, Venkatachalam KV, Croteau R (1985). "Metabolism of monoterpenes: oxidation of isopiperitenol to isopiperitenone, and subsequent isomerization to piperitenone by soluble enzyme preparations from peppermint (Mentha piperita) leaves". Arch. Biochem. Biophys. 238 (1): 49–60. doi:10.1016/0003-9861(85)90139-0. PMID 3885858.
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