LCOR

Function

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000196233 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N, Mader S, Han VK, Yang XJ, White JH (Jan 2003). "Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms". Mol Cell. 11 (1): 139–50. doi:10.1016/S1097-2765(03)00014-5. PMID 12535528.
  4. White JH, Fernandes I, Mader S, Yang XJ (Jun 2004). "Corepressor recruitment by agonist-bound nuclear receptors". Vitam Horm. Vitamins & Hormones. 68: 123–43. doi:10.1016/S0083-6729(04)68004-6. ISBN 9780127098685. PMID 15193453.
  5. "Entrez Gene: LCOR ligand dependent nuclear receptor corepressor".

Further reading

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Ligand-dependent corepressor



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