List of Dutch Top 40 number-one singles of 1980

Note: The flag placed next to the artist's name indicates material is of that country's origin.

Issue Date	Song	Artist(s)	Reference
5 January	"Weekend"	Earth and Fire	[1]
12 January	"I Have a Dream"	ABBA	[2]
19 January			[3]
26 January			[4]
2 February	"Rapper's Delight"	The Sugarhill Gang	[5]
9 February			[6]
16 February			[7]
23 February	"Crying"	Don McLean	[8]
1 March			[9]
8 March			[10]
15 March			[11]
22 March			[12]
29 March	"Pearlydumm"	BZN	[13]
5 April	"Sajang é"	Massada	[14]
12 April			[15]
19 April	"You and Me"	Spargo	[16]
26 April			[17]
3 May			[18]
10 May	"Sun of Jamaica"	Goombay Dance Band	[19]
17 May			[20]
24 May			[21]
31 May	"Funkytown"	Lipps Inc	[22]
7 June			[23]
14 June			[24]
21 June	"Cara Mia"	Jay and the Americans	[25]
28 June			[26]
5 July			[27]
12 July	"Late at Night"	Maywood	[28]
19 July			[29]
26 July			[30]
2 August	"Xanadu"	Olivia Newton-John and Electric Light Orchestra	[31]
9 August			[32]
16 August			[33]
23 August	"The Winner Takes It All"	ABBA	[34]
30 August			[35]
6 September			[36]
13 September			[37]
20 September			[38]
27 September			[39]
4 October	"One Day I'll Fly Away"	Randy Crawford	[40]
11 October			[41]
18 October	"Woman in Love"	Barbra Streisand	[42]
25 October			[43]
1 November			[44]
8 November			[45]
15 November			[46]
22 November			[47]
29 November	"Never Knew Love Like This Before"	Stephanie Mills	[48]
6 December	"Super Trouper"	ABBA	[49]
13 December			[50]
20 December	"Santa Maria"	Roland Kaiser	[51]
27 December	No Top 40 released

These hits topped the Dutch Top 40 in 1980.