M. Madan Babu

Babu grew up in Chennai, India.[5] He became interested in learning to program as a young child when his father brought home a personal computer.[5] Babu was introduced to biotechnology as a high school student.[5] He obtained his Bachelor of Technology degree from Anna University, where he was introduced to the field of computational biology.[5] Babu obtained his PhD in computational genomics at the University of Cambridge supervised by Sarah Teichmann in 2004.[2]

After his PhD, Babu was a postdoctoral researcher at the National Center for Biotechnology Information (NCBI), at the National Institute of Health (NIH) in Bethesda, Maryland with Aravind L. Iyer. In 2006, he became a group leader at the MRC Laboratory of Molecular Biology in Cambridge, UK. In July 2020, Babu joined the faculty of St. Jude Children’s Research Hospital as the endowed chair in biological data science in the structural biology department and director of the center of excellence for data-driven discovery.[6]

Babu's research focuses on understanding the regulation of cellular systems at varying scales, including molecular, system, and genomic levels.[1] He also studies the effects of such regulation on genome evolution.[5][7] In particular, his research group studies G protein-coupled receptors and intrinsically disordered proteins using a combination of computational biology and experimental biology approaches.[8][9]

As of 2020 Babu serves as chief editor of the journal Molecular Systems Biology.[7][10]