MOBKL1A

Mps one binder kinase activator-like 1A, also known as Mob1 homolog 1A, is a protein that in humans is encoded by the MOBKL1A gene.[4][5]

MOB1B
Identifiers
AliasesMOB1B, MATS2, MOB4A, MOBKL1A, MOB kinase activator 1B
External IDsOMIM: 609282 MGI: 1915723 HomoloGene: 61676 GeneCards: MOB1B
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4q13.3Start70,902,326 bp[1]
End71,022,449 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

92597

68473

Ensembl

ENSG00000173542

ENSMUSG00000006262

UniProt

Q7L9L4

Q8BPB0

RefSeq (mRNA)

NM_001244766
NM_001244767
NM_173468

NM_026735

RefSeq (protein)

NP_001231695
NP_001231696
NP_775739

NP_081011

Location (UCSC)Chr 4: 70.9 – 71.02 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation.[4]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000173542 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: MOB1".
  5. Devroe E, Erdjument-Bromage H, Tempst P, Silver PA (June 2004). "Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444–51. doi:10.1074/jbc.M401999200. PMID 15067004.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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