Martin Landray

Martin Landray is a British physician, epidemiologist and data scientist who serves as a Professor of Emerging Infectious Diseases and Global Health at the University of Oxford. Landray has specialist knowledge and experience at designing, conducting and analysing large-scale randomised control trials; including practice-changing international trials that have recruited over 65,000 individuals.[1]

Martin Landray
Alma materUniversity of Birmingham
Scientific career
InstitutionsUniversity of Oxford
Websitewww.bdi.ox.ac.uk/Team/martin-landray

Landray serves as co-chief investigator of the RECOVERY Trial into treatment drugs for COVID-19 (the largest such clinical trial in the world) alongside Peter Horby.[2][3][4] In June 2020, the trial discovered the first known life-saving COVID-19 drug, Dexamethasone.[5][6][7] The trial was first to find negative results for Hydroxychloroquine[8] and Lopinavir/ritonavir.[9] The trial continues to study Azithromycin, Tocilizumab, Convalescent plasma and REGN-COV2.[10]

Landray has previously helped analyse data for the UK Biobank on over half a million people,[11] been one of the leaders of CTTI’s mobile clinical trial project[12] and has driven work in 2013 to create new FDA guidelines for clinical trials.[13]

Positions held

Landray holds the following positions:[14]

  • Research Director, Health Data Research UK
  • Acting Director, Big Data Institute
  • Lead, Big Data & Computing Innovation, MRC Population Health Research Unit
  • Lead, Clinical Informatics & Big Data, NIHR Oxford Biomedical Research Centre
  • Lead, Health Informatics Hub, UK Biobank
  • Honorary Consultant Physician, Oxford University Hospitals NHS Foundation Trust
  • Member of the Steering Committee of the FDA Clinical Trial Transformation Initiative
  • Member of the NHS Digital Research Advisory Group
  • Member of the NICE Data & Analytics External Reference Group
  • Lead of the 21st Century Clinical Trials programme for Health Data Research UK

References

  1. "Why the UK is ahead of the curve in the global race to find coronavirus treatments - Q&A with Martin Landray". Reaction. 22 April 2020.
  2. "ISRCTN - ISRCTN50189673: A randomised trial of treatments to prevent death in patients hospitalised with COVID-19 (coronavirus)". www.isrctn.com. Retrieved 2020-09-06.
  3. "Large-scale trial for coronavirus drugs launches in UK". Clinical Trials Arena. 6 April 2020. Retrieved 7 September 2020.
  4. "Managing clinical trials during the pandemic — Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences". www.ndorms.ox.ac.uk. Retrieved 7 September 2020.
  5. "Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 | University of Oxford". www.ox.ac.uk. Retrieved 2020-09-06.
  6. "Prime Minister's statement on coronavirus (COVID-19): 16 June 2020". GOV.UK. Retrieved 2020-09-06.
  7. Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. (July 2020). "Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report". The New England Journal of Medicine. 0. doi:10.1056/NEJMoa2021436. PMC 7383595. PMID 32678530.
  8. Group, The RECOVERY Collaborative (8 October 2020). "Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19". New England Journal of Medicine. 383 (21): 2030–2040. doi:10.1056/NEJMoa2022926. PMC 7556338. PMID 33031652. Retrieved 16 October 2020.
  9. Horby, Peter W.; Mafham, Marion; Bell, Jennifer L.; Linsell, Louise; Staplin, Natalie; Emberson, Jonathan; Palfreeman, Adrian; Raw, Jason; Elmahi, Einas; Prudon, Benjamin; Green, Christopher; Carley, Simon; Chadwick, David; Davies, Matthew; Wise, Matthew P.; Baillie, J. Kenneth; Chappell, Lucy C.; Faust, Saul N.; Jaki, Thomas; Jefferey, Katie; Lim, Wei Shen; Montgomery, Alan; Rowan, Kathryn; Juszczak, Edmund; Haynes, Richard; Landray, Martin J. (5 October 2020). "Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial". The Lancet. 0 (10259): 1345–1352. doi:10.1016/S0140-6736(20)32013-4. ISSN 0140-6736. PMC 7535623. PMID 33031764. Retrieved 16 October 2020.
  10. "Welcome — RECOVERY Trial". www.recoverytrial.net. Retrieved 16 October 2020.
  11. "The challenge of saving lives with 'big data'". BBC News. 7 February 2016. Retrieved 16 October 2020.
  12. Entis, Laura (27 January 2016). "Can smartphone drug trials improve medical care?". The Guardian. Retrieved 16 October 2020.
  13. (PDF) http://eurheartj.oxfordjournals.org/content/ehj/34/41/3161.full.pdf. Retrieved 16 October 2020. Cite journal requires |journal= (help); Missing or empty |title= (help)
  14. "Martin Landray — Nuffield Department of Population Health". www.ndph.ox.ac.uk. Retrieved 16 October 2020.
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