NLRP8

NLRP8, short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals.[3][4] It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.

NLRP8
Identifiers
AliasesNLRP8, CLR19.2, NALP8, NOD16, PAN4, NLR family, pyrin domain containing 8, NLR family pyrin domain containing 8
External IDsOMIM: 609659 HomoloGene: 82360 GeneCards: NLRP8
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.43Start55,947,832 bp[1]
End55,988,629 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

126205

n/a

Ensembl

ENSG00000179709

n/a

UniProt

Q86W28

n/a

RefSeq (mRNA)

NM_176811
NM_001317000

n/a

RefSeq (protein)

NP_001303929
NP_789781

n/a

Location (UCSC)Chr 19: 55.95 – 55.99 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

References

  1. GRCh38: Ensembl release 89: ENSG00000179709 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Ponsuksili S, Brunner RM, Goldammer T, et al. (March 2006). "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. doi:10.1095/biolreprod.105.045096. PMID 16339045.
  4. Tian X, Pascal G, Monget P (2009). "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9: 202. doi:10.1186/1471-2148-9-202. PMC 2735741. PMID 19682372.

Further reading


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