Orthocaine

Orthocaine
Names
	Preferred IUPAC name 3-Amino-4-hydroxybenzoic acid methyl ester
	Systematic IUPAC name Methyl 3-amino-4-hydroxybenzoate
	Other names aminobenz
Identifiers
CAS Number	536-25-4 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	3-14-00-01477
ChemSpider	10358;
ECHA InfoCard	100.007.845
EC Number	208-627-3;
KEGG	C14171;
PubChem CID	10815;
UNII	JK16YI13QK ;
CompTox Dashboard (EPA)	DTXSID2060208 ;
	InChI InChI=1S/C8H9NO3/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4,10H,9H2,1H3 Key: VNQABZCSYCTZMS-UHFFFAOYSA-N;
	SMILES COC(=O)C1=CC(N)=C(O)C=C1;
Properties
Chemical formula	C8H9NO3
Molar mass	167.16196
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Orthocaine is a local anesthetic. Developed in the 1890s, it was found to be of limited use due to its low solubility in water, but it has been used in powdered form to dust onto painful wounds.[1][2][3]

References

Walter Sneader (23 June 2005). Drug Discovery: A History. John Wiley & Sons. pp. 127–9. ISBN 978-0-471-89979-2.
Rajbir Singh (2002). Synthetic Drugs. Mittal Publications. pp. 167–8. ISBN 978-81-7099-831-0.
Stanley Alstead (22 October 2013). Poulsson's Text-Book of Pharmacology and Therapeutics. Elsevier. pp. 104–5. ISBN 978-1-4832-2584-5.

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[Sneader2005-1] Walter Sneader (23 June 2005). Drug Discovery: A History. John Wiley & Sons. pp. 127–9. ISBN 978-0-471-89979-2.

[Singh2002-2] Rajbir Singh (2002). Synthetic Drugs. Mittal Publications. pp. 167–8. ISBN 978-81-7099-831-0.

[Alstead2013-3] Stanley Alstead (22 October 2013). Poulsson's Text-Book of Pharmacology and Therapeutics. Elsevier. pp. 104–5. ISBN 978-1-4832-2584-5.