Presqualene diphosphate synthase

Presqualene diphosphate synthase (EC 2.5.1.103, SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming).[1] This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate presqualene diphosphate + diphosphate
Presqualene diphosphate synthase
Identifiers
EC number2.5.1.103
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

References

  1. Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J (2011). "Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii". Proc. Natl. Acad. Sci. USA. 108 (30): 12260–12265. doi:10.1073/pnas.1106222108. PMC 3145686. PMID 21746901.
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