Spur cell hemolytic anemia

Spur cell hemolytic anemia, is a form of hemolytic anemia that results secondary to severe impaired liver function or cirrhosis, and is mostly seen in alcoholics. Chronic liver disease impairs the liver's ability to esterify cholesterol, causing free cholesterol to bind to the red cell membrane, increasing its surface area without increasing its volume. This condition also creates rough or thorny projections on the erythrocyte named acanthocytes.[1]

See also

References
  1. "Spur-cell hemolytic anemia in severe alcoholic cirrhosis". Journal of the American Society of Hematology. The American Society of Hematology. January 1, 2003. Retrieved 10 April 2011.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.