Succinylsulfathiazole

Succinylsulfathiazole (also known as sulfasuxidine) is a sulfonamide. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water.

Succinylsulfathiazole

Clinical data
ATC code	A07AB04 (WHO)
Identifiers
IUPAC name 4-oxo-4-({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)butanoic acid
CAS Number	116-43-8
PubChem CID	5315
UNII	RSS8647O4S
KEGG	D07060 Y
ChEMBL	ChEMBL1484857
CompTox Dashboard (EPA)	DTXSID7045281
ECHA InfoCard	100.003.765
Chemical and physical data
Formula	C13H13N3O5S2
Molar mass	355.38 g·mol−1
3D model (JSmol)	Interactive image
SMILES OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
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It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to Sulfathiazole and is absorbed.

The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses.

The Succinyl group is attached to form a Prodrug for Controlled release of drug Sulphathiazole.