Succinylsulfathiazole

Succinylsulfathiazole (also known as sulfasuxidine) is a sulfonamide. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water.

Succinylsulfathiazole
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.003.765
Chemical and physical data
FormulaC13H13N3O5S2
Molar mass355.38 g·mol−1
3D model (JSmol)
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It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to Sulfathiazole and is absorbed.

The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses.

The Succinyl group is attached to form a Prodrug for Controlled release of drug Sulphathiazole.


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