UDP-N-acetyl-D-mannosamine dehydrogenase

UDP-N-acetyl-D-mannosamine dehydrogenase (EC 1.1.1.336, UDP-ManNAc 6-dehydrogenase, wecC (gene)) is an enzyme with systematic name UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+
UDP-N-acetyl-D-mannosamine dehydrogenase
Identifiers
EC number1.1.1.336
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme participates in acetamido sugar biosynthesis in bacteria and archaea.

References

  1. Namboori SC, Graham DE (April 2008). "Acetamido sugar biosynthesis in the Euryarchaea". Journal of Bacteriology. 190 (8): 2987–96. doi:10.1128/JB.01970-07. PMC 2293230. PMID 18263721.
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