Varinder Aggarwal

Varinder Kumar Aggarwal FRS (born 1961) is a British organic chemist specialising in asymmetric synthesis. He is a Professor of Synthetic Chemistry at the School of Chemistry of the University of Bristol.[4][5]

Varinder Kumar Aggarwal
Born1961 (age 59–60) [1]
Kalianpur, Uttar Pradesh, India [2]
Alma mater
Awards
Scientific career
FieldsOrganic chemistry, Asymmetric synthesis
Institutions
ThesisStereocontrolled synthesis with phenylthio migration (1986)
Doctoral advisorStuart Warren

Early life

Aggarwal was born in 1961 in Kalianpur, a town in Northern India. In 1963 his family emigrated to the United Kingdom. He was one of six sons, and grew up in Scotland, then Nottingham, England.[2]

Education and career

Aggarwal earned his PhD from the University of Cambridge in 1986 under the supervision of Stuart Warren. His thesis was entitled Stereocontrolled synthesis with phenylthio migration.[3][6] He carried out postdoctoral work with Gilbert Stork at Columbia University, before taking up appointments first in Bath, then Sheffield and finally at the University of Bristol where he is currently a professor.

Research

Aggarwal developed new methods of using chemical reactions to assemble complex, biologically important molecules. His research includes new ways of speeding up, or catalysing, these processes of synthesis. His work has applications in medicine, such as helping to provide a more effective vaccine against tuberculosis.

Although many organic molecules can occur in "right-handed" and "left-handed" forms, invariably just one of these is seen in living organisms. Normal chemical reactions, however, make both forms in equal amounts. Aggarwal's work on asymmetric synthesis made it possible to selectively synthesise more of the form important to understanding biological processes.

Aggarwal specialises in a type of molecule called ylides, which are important to the Wittig reaction – a standard tool in organic chemistry.[7]

Awards and honours

Aggarwal is the winner of multiple awards, including the Corday-Morgan and Organic Stereochemistry awards of the Royal Society of Chemistry. He was elected a Fellow of the Royal Society (FRS) in 2012.[7] His certificate of election reads:

Aggarwal is distinguished for his outstanding contributions to the field of asymmetric synthesis, particularly applications of ylide chemistry where he is the world leader. The important new methodology he has developed has been complemented by detailed mechanistic studies which have brought about improved understanding of many fundamental reactions. His innovative approach is highlighted by the unusual but highly effective reactions of sulphur ylides with boranes, an area that has much scope for future development. His productivity and breadth make him one of the foremost organic chemists of his generation and one who is very widely recognised internationally.[5]

References
  1. Organic Stereochemistry Award 2009 winner. Royal Society of Chemistry.
  2. "Profile". Organic & Biomolecular Chemistry. 1 (4): 1–2. 2003. doi:10.1039/b301090m. ISSN 1477-0520.
  3. Varinder Kumar Aggarwal. University of Bristol. Retrieved 2016-03-30.
  4. Professor Varinder Aggarwal. University of Bristol. Retrieved 2016-03-30.
  5. "EC/2012/01: Aggarwal, Varinder Kumar". The Royal Society. Retrieved 30 March 2016.
  6. EthOS, British Library. Retrieved 2016-03-30.
  7. "Varinder Aggarwal". London: Royal Society. One or more of the preceding sentences may incorporate text from the royalsociety.org website where "all text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." "Terms, conditions and policies". Archived from the original on 20 February 2016. Retrieved 9 March 2016.
  8. "Davy Medallist 2019". Royal Society. Retrieved 5 October 2019.
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