WNT9B

WNT9B
Identifiers
Aliases	WNT9B, WNT14B, WNT15, Wnt family member 9B
External IDs	OMIM: 602864 MGI: 1197020 HomoloGene: 2551 GeneCards: WNT9B
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	46,886,730 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	103,749,821 bp[2]
Gene ontology
Molecular function	• GO:0005110 frizzled binding; • receptor binding; • co-receptor binding; • receptor ligand activity;
Cellular component	• extracellular region; • extracellular;
Biological process	• kidney morphogenesis; • cell-cell signaling; • cellular response to starvation; • mesonephric duct formation; • multicellular organism development; • male genitalia development; • cornea development in camera-type eye; • branching morphogenesis of an epithelial tube; • kidney rudiment formation; • collecting duct development; • regulation of asymmetric cell division; • embryonic cranial skeleton morphogenesis; • kidney development; • Wnt signaling pathway, planar cell polarity pathway; • cellular response to retinoic acid; • mesenchymal stem cell maintenance involved in nephron morphogenesis; • establishment of planar polarity involved in nephron morphogenesis; • nephron tubule morphogenesis; • palate development; • metanephric tubule development; • in utero embryonic development; • regulation of tube size; • mesonephric tubule development; • uterus morphogenesis; • response to retinoic acid; • regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; • cell fate commitment; • branching involved in ureteric bud morphogenesis; • GO:0048554 positive regulation of catalytic activity; • metanephric tubule formation; • regulation of protein phosphorylation; • negative regulation of stem cell population maintenance; • midbrain dopaminergic neuron differentiation; • non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation; • Wnt signaling pathway; • neuron differentiation; • regulation of receptor activity; • canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7484
	22412
	ENSG00000158955; ENSG00000276799
	ENSMUSG00000018486
	O14905
	O35468
	NM_003396; NM_001320458
	NM_011719
	NP_001307387; NP_003387
	NP_035849
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Wnt-9b (formerly Wnt15[5]) is a protein that in humans is encoded by the WNT9B gene.[6]

References

ENSG00000276799 GRCh38: Ensembl release 89: ENSG00000158955, ENSG00000276799 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000018486 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Garriock RJ, Warkman AS, Meadows SM, D'Agostino S, Krieg PA (2007). "Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16". Developmental Dynamics. 236 (5): 1249–58. doi:10.1002/dvdy.21156. PMID 17436276. S2CID 21016668.
"Entrez Gene: Wnt9b wingless-type MMTV integration site family, member 9B".

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[refGRCh38Ensembl-1] ENSG00000276799 GRCh38: Ensembl release 89: ENSG00000158955, ENSG00000276799 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018486 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Garriock RJ, Warkman AS, Meadows SM, D'Agostino S, Krieg PA (2007). "Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16". Developmental Dynamics. 236 (5): 1249–58. doi:10.1002/dvdy.21156. PMID 17436276. S2CID 21016668.

[entrez-6] "Entrez Gene: Wnt9b wingless-type MMTV integration site family, member 9B".

Signaling pathway: Wnt signaling pathway
Ligand	WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16
Receptor	Frizzled LRP5 LRP6
Second messenger	Dishevelled GSK-3 APC Beta-catenin