Wellcome Trust

The Trust funds or co-funds a number of major biomedical research initiatives:[13]

• Avon Longitudinal Study of Parents and Children (ALSPAC), a cohort study of children born in England during 1991 and 1992.
• The Cancer Genome Project at the Wellcome Trust Sanger Institute.
• The Diamond Light Source, the UK's national synchrotron science facility in Oxfordshire.
• Developing Excellence in Leadership, Training and Science Initiative (DELTAS), a collaboration with the Department for International Development (DFID) to establish cutting-edge research and training programmes across the African continent.
• The Ebola Emergency Initiative, a fast-tracked research programme with the goal of identifying clinical and public health interventions to counter the West African Ebola Epidemic.
• The Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory facilitates research into the genetic component of type 1 diabetes and is based in the Cambridge Institute for Medical Research.
• The Seeding Drug Discovery Initiative.
• The Structural Genomics Consortium, an international organisation focussing on three-dimensional structures of proteins of medical relevance with an emphasis on open data.
• The Wellcome Trust Sanger Institute, a non-profit, British genomics and genetics research institute.[14]
• UK Biobank and the UK Biobank Ethics and Governance Council.

• The KEMRI-Wellcome Trust Research Programme, established in 1989 in partnership with the Kenya Medical Research Institute.[15]
• The Malawi-Liverpool-Wellcome Trust Clinical Research Programme, established in 1995.
• The Africa Centre for Health and Population Studies in South Africa, established in 1998 in partnership with the South African Medical Research Council.
• The Wellcome Trust-Mahidol University-Oxford Tropical Medicine Research Programme in partnership with the Faculty of Tropical Medicine, Mahidol University, researching in Thailand and Laos and established in 1979.
• The Vietnam Research Programme and Oxford University Clinical Research Unit in Ho Chi Minh City and Hanoi.

Also known as SDDI, this five-year initiative started in October 2005 with the remit "to facilitate the development of drug-like small molecules that address unmet medical needs." SDDI was based in London and managed by Richard Davis.[16] Through early 2010, SDDI had provided more than £80 million across 30 projects split between academic institutions and companies.[16] To early 2010, all but one of the company recipients were either start-ups or spin-outs.[16] In May 2010, an additional £110 million was added to the SDDI fund with the intent to extend the initiative for an additional 5 years.[17]

Wellcome Trust announced the need for at least $8 billion of new funding for research, development, and supply of treatments related to COVID-19. [18]

In September 2019, Wellcome launched an initiative to reimagine research and improve the culture in which research is conducted. Current incentive structures and, as a result, culture and practices, prioritise publication outputs above all else. This is damaging people's wellbeing and undermining the quality of research itself.[19]

The Wellcome Trust plays an important role in encouraging publication of research in open access repositories[20] such as Europe PubMed Central (EuropePMC). The Wellcome Trust believes that maximising the distribution of these papers - by providing free, online access - is the most effective way of ensuring that the research can be accessed, read and built upon. In turn, this will foster a richer research culture.

In 2016, the Wellcome Trust partnered with the US National Institutes of Health (NIH) and the Howard Hughes Medical Institute to launch the Open Science Prize[21] to "help develop services, tools and platforms that enable open content to be discovered, assessed and re-used in ways that will advance discovery and spark innovation."[21]

In 2016, Wellcome Trust announced that it would be launching Wellcome Open Research,[22] an open access publication system running on the F1000 Research platform.[23] Article processing charges will be covered directly by Wellcome Trust. Papers from the system are now indexed in PubMed Central.[24]

In the summer of 2015, the Wellcome Trust joined the Japanese government, 7 Japanese pharmaceutical and diagnostics companies, The Bill and Melinda Gates Foundation, and the United Nations Development Program as funding partner of the Global Health Innovative Technology Fund (GHIT), which funds scientific research and development for anti-infectives and diagnostics for diseases that primarily affect the developing world.[25][26]

In June 2007, the Wellcome Building reopened after refurbishment as a public venue, housing the Wellcome Collection, the Wellcome Trust Centre for the History of Medicine at University College London and the Wellcome Library.[27] The aim of the Wellcome Collection is to enhance public understanding of medical science and history. The building contains gallery spaces, conference facilities, space for debates, drama and workshops, a café and a bookshop. The galleries show a small sample of works from Sir Henry Wellcome's collection, and host a programme of events and exhibitions. The Wellcome Collection and exhibitions are open to the public free of charge six days a week.[28]

The Wellcome Collection and Wellcome Library are members of The London Museums of Health & Medicine.

The Wellcome Trust runs an annual photography prize which aims to explore "the human side of three urgent health challenges". Judges in 2021 include Dr Dixon Chabanda, Sir Jeremy Farrar, Dr Katerina Srahulkova and Azu Nwagbogu. Winners in each category receive a prize of £10,000.

The Wellcome Trust sponsors an annual book prize, the Wellcome Book Prize, which "aims to excite public interest and encourage debate" around medicine and health.[29]

In June 2019, Wellcome released the results of the 2018 global survey on public attitudes toward science and health. Topics include trust of scientists, doctors, and nurses; religion and science, and vaccines, among others.[30] It was Wellcome's first Global Monitor and was intended to "provide robust evidence on how public attitudes vary across different demographic groups and countries."[31]