Zinc finger protein 208

ZNF208
Identifiers
Aliases	ZNF208, PMIDP, ZNF95, zinc finger protein 208
External IDs	OMIM: 603977 MGI: 1917477 HomoloGene: 133818 GeneCards: ZNF208
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	22,010,949 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	39,540,420 bp[2]
Gene ontology
Molecular function	• DNA binding; • zinc ion binding; • metal ion binding; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• intracellular; • cell nucleus;
Biological process	• regulation of transcription, DNA-templated; • transcription, DNA-templated; • regulation of transcription from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	7757
	70227
	ENSG00000160321
	ENSMUSG00000068959
	O43345
	n/a
	NM_001329971; NM_001329972; NM_001329973; NM_001329974; NM_007153
	NM_001004139
	NP_001316900; NP_001316901; NP_001316902; NP_001316903; NP_009084
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 208 is a protein that in humans is encoded by the ZNF208 gene. [5]

Function

Zinc finger proteins (ZNFs), such as ZNF208, bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. A conserved protein motif, termed the Kruppel-associated box (KRAB) domain, mediates protein-protein interactions (Eichler et al., 1998 [PubMed 9724325]). See ZNF91 (MIM 603971) for further information on ZNFs.

References

GRCh38: Ensembl release 89: ENSG00000160321 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000068959 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger protein 208". Retrieved 2016-01-28.

Zinc finger protein 208

Function

References

Further reading