(+)-sabinene synthase

(+)-sabinene synthase (EC 4.2.3.110, SS) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (+)-sabinene-forming).[1][2] This enzyme catalyses the following chemical reaction

geranyl diphosphate (+)-sabinene + diphosphate
(+)-sabinene synthase
Identifiers
EC number4.2.3.110
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from Salvia officinalis (sage).

References

  1. Wise ML, Savage TJ, Katahira E, Croteau R (June 1998). "Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase". The Journal of Biological Chemistry. 273 (24): 14891–9. doi:10.1074/jbc.273.24.14891. PMID 9614092.
  2. Peters RJ, Croteau RB (September 2003). "Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases". Archives of Biochemistry and Biophysics. 417 (2): 203–11. doi:10.1016/s0003-9861(03)00347-3. PMID 12941302.
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