1L-myo-inositol 1-phosphate cytidylyltransferase

1L-myo-inositol 1-phosphate cytidylyltransferase (EC 2.7.7.74, CTP:inositol-1-phosphate cytidylyltransferase (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)), IPCT (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)), L-myo-inositol-1-phosphate cytidylyltransferase) is an enzyme with systematic name CTP:1L-myo-inositol 1-phosphate cytidylyltransferase.[1] This enzyme catalyses the following chemical reaction

CTP + 1L-myo-inositol 1-phosphate diphosphate + CDP-1L-myo-inositol
1L-myo-inositol 1-phosphate cytidylyltransferase
Identifiers
EC number2.7.7.74
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate.

References

  1. Rodrigues MV, Borges N, Henriques M, Lamosa P, Ventura R, Fernandes C, Empadinhas N, Maycock C, da Costa MS, Santos H (August 2007). "Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles". Journal of Bacteriology. 189 (15): 5405–12. doi:10.1128/JB.00465-07. PMC 1951816. PMID 17526717.
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