Absorption rate constant

The absorption rate constant Ka is a value used in pharmacokinetics to describe the rate at which a drug enters into the system. It is expressed in units of time−1.[1] The Ka is related to the absorption half-life (t1/2a) per the following equation: Ka = ln(2) / t1/2a.[1]

Ka values can typically only be found in research articles.[2] This is in contrast to parameters like bioavailability and elimination half-life, which can often be found in drug and pharmacology handbooks.[2]

References

  1. John E. Murphy (1 July 2016). Clinical Pharmacokinetics. ASHP. pp. 26–. ISBN 978-1-58528-538-9.
  2. Miles Hacker; William S. Messer; Kenneth A. Bachmann (19 June 2009). Pharmacology: Principles and Practice. Academic Press. pp. 257–. ISBN 978-0-08-091922-5.


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