CDP-glycerol glycerophosphotransferase
In enzymology, a CDP-glycerol glycerophosphotransferase (EC 2.7.8.12) is an enzyme that catalyzes the chemical reaction
- CDP-glycerol + (glycerophosphate)n CMP + (glycerophosphate)n+1
| CDP-glycerol glycerophosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.8.12 | ||||||||
| CAS number | 9076-71-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are CDP-glycerol and (glycerophosphate)n, whereas its two products are CMP and (glycerophosphate)n+1.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase. Other names in common use include teichoic-acid synthase, cytidine diphosphoglycerol glycerophosphotransferase, poly(glycerol phosphate) polymerase, teichoic acid glycerol transferase, glycerophosphate synthetase, and CGPTase.
References
- BURGER MM, GLASER L (1964). "THE SYNTHESIS OF TEICHOIC ACIDS. I. POLYGLYCEROPHOSPHATE". J. Biol. Chem. 239: 3168–77. PMID 14245357.
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