Eugenol synthase
Eugenol synthase (EC 1.1.1.318, LtCES1, EGS1, EGS2) is an enzyme with systematic name eugenol:NADP+ oxidoreductase (coniferyl ester reducing).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction: eugenol + a carboxylate + NADP+ a coniferyl ester + NADPH + H+
Eugenol synthase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.318 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The enzyme acts in the reverse direction.
References
- Koeduka T, Fridman E, Gang DR, Vassão DG, Jackson BL, Kish CM, Orlova I, Spassova SM, Lewis NG, Noel JP, Baiga TJ, Dudareva N, Pichersky E (June 2006). "Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester". Proceedings of the National Academy of Sciences of the United States of America. 103 (26): 10128–33. doi:10.1073/pnas.0603732103. PMC 1502517. PMID 16782809.
- Vassão DG, Kim SJ, Milhollan JK, Eichinger D, Davin LB, Lewis NG (September 2007). "A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeugenol". Archives of Biochemistry and Biophysics. 465 (1): 209–18. doi:10.1016/j.abb.2007.06.002. PMID 17624297.
- Louie GV, Baiga TJ, Bowman ME, Koeduka T, Taylor JH, Spassova SM, Pichersky E, Noel JP (October 2007). "Structure and reaction mechanism of basil eugenol synthase". PLOS ONE. 2 (10): e993. doi:10.1371/journal.pone.0000993. PMC 1991597. PMID 17912370.
- Koeduka T, Louie GV, Orlova I, Kish CM, Ibdah M, Wilkerson CG, Bowman ME, Baiga TJ, Noel JP, Dudareva N, Pichersky E (May 2008). "The multiple phenylpropene synthases in both Clarkia breweri and Petunia hybrida represent two distinct protein lineages". The Plant Journal. 54 (3): 362–74. doi:10.1111/j.1365-313X.2008.03412.x. PMC 2741023. PMID 18208524.
- Koeduka T, Baiga TJ, Noel JP, Pichersky E (January 2009). "Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain". Plant Physiology. 149 (1): 384–94. doi:10.1104/pp.108.128066. PMC 2613694. PMID 18987218.
- Gupta AK, Schauvinhold I, Pichersky E, Schiestl FP (December 2014). "Eugenol synthase genes in floral scent variation in Gymnadenia species" (PDF). Functional & Integrative Genomics. 14 (4): 779–88. doi:10.1007/s10142-014-0397-9. PMID 25239559.
External links
- Eugenol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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