Final Fight: Streetwise

Kyle and Cody Travers are brothers who take part in the sport of underground fighting. As Cody Travers' younger brother, Kyle is the star of the underground Metro City fight club, spending nights fighting various other fighters in order to earn enough quick cash to make ends meet. After the end of a fight one evening, Kyle and Cody decide to meet at the local bar to celebrate with some beers and a round of pool; however, Cody has some unspoken business that delays his arrival for an hour. After Kyle arrives at the bar, he plays a game with his girlfriend and bar owner Vanessa Sims (whose brother is a member of the police department), while waiting for Cody. Kyle later finds out that Cody is using a powerful strength-enhancing drug called "glow", which helps the arthritis in his knees. Kyle later discovers that glow is being made by a psychotic priest named Father Bella, who hopes to use the drug to bring about the apocalypse. When Kyle finds Bella on the roof of his church, Cody is with him, mutated by a concentrated dose of glow. It is later revealed that Bella is actually the younger brother of Belger, the antagonist of the original game, just before he and Kyle begin to fight.

During the battle, Cody regains his senses, and throws himself and Bella off the roof landing in the courtyard. Bella regains consciousness from the fall and begins to reach for his handgun but is stopped by Kyle. Bella utters his last words "I am your savior," before Kyle fires a fatal shot directly to the former's head, replying "You're nothing." Afterward he finds Cody unconscious from the fall.

Some time later, Kyle and Cody wake up in the hospital, where they meet with Vanessa whose brother was killed during the final battles; she holds onto her late brother's badge in his memory. Cody's arthritis is now gone and he seems eager to resume fighting. Kyle notices Dr. Chang, the creator of "glow", leaving the police station on the local news and mentions he has a feeling this might not be over quite yet.

The game's protagonist is Kyle Travers, younger brother of Cody Travers from the original Final Fight. He is a 27-year-old former Marine who has lived on the streets of Metro City, along with Cody, since childhood. Coming from a broken family, Kyle was brought up by his brother, who taught him how to survive life on the streets and earn respect. Haggar reveals that Kyle was a troublemaker and hoodlum prior to joining the military, calling him a "skinny legged punk". Later, as a skilled hand-to-hand fighter, Kyle uses his talent to support himself in the local pit fighting club. He goes in search of Cody after he is abducted from Kyle's girlfriend's bar. His girlfriend, Vanessa Sims, and her brother, Sergeant Sims, aid Kyle in his search by providing him with information as they get it.

Enemies include 2P, Andore (voiced by Gerardo Sprigg)[1] and Cammy. The game's antagonist is Father Bella. He has been distributing a new drug called GLOW throughout Metro City. It is later revealed that he is the younger brother of Belger, the antagonist of the original Final Fight.

Poison, a controversial female character from the original Final Fight and Final Fight Revenge, was originally planned to be in the game. This fact is known, because there is some concept art of Poison, which shows her with red hair, which originally belonged to her pallet swap, Roxy. It is unknown what role she was supposed to play in the game, including whether she was supposed to be an enemy or not. It is unknown why she was cut from the final version of the game.

As well as remixes of the original game's themes, the soundtrack was provided by RZA, Mos Def, Fear Factory, Slipknot, Soulfly, Dub Pistols, Shadows Fall, Opeth, Lil' Flip, Nappy Roots, Dujeous and Gizmachi.