GDP-D-glucose phosphorylase
GDP-D-glucose phosphorylase (EC 2.7.7.78) is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction
- GDP-alpha-D-glucose + phosphate alpha-D-glucose 1-phosphate + GDP
| GDP-D-glucose phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.78 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates.
References
- Adler LN, Gomez TA, Clarke SG, Linster CL (June 2011). "A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals". The Journal of Biological Chemistry. 286 (24): 21511–23. doi:10.1074/jbc.m111.238774. PMC 3122210. PMID 21507950.
External links
- GDP-D-glucose+phosphorylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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