Junko Enoshima

In the first game, Danganronpa: Trigger Happy Havoc, Junko fakes her death by having Mukuro pose as her so she can kill her under her Monokuma guise, using the event to encourage her former classmates at Hope's Peak Academy to participate in a "killing game", both actions serving to feed her desire to fuel an "ultimate despair" within herself and them.[6] Throughout the game, Junko (in the form of a robotic stuffed bear dubbed Monokuma) provides various motives to turn the students against one another, overseeing the subsequent class trials and performing the various executions while broadcasting the events to the world at large, culminating in her presenting Mukuro's corpse in an attempt to frame the "Ultimate Detective" Kyoko Kirigiri without breaking the rules she set for herself for the "killing game", and ultimately agreeing to execute herself after being exposed as the mastermind.

In Danganronpa 2: Goodbye Despair, Junko is revealed to have used Chihiro's Alter Ego technology to transfer her consciousness into Monokuma at the moment of her death as an A.I. (explaining their reactivation in the prior game's post-credits scene), hijacking the Future Foundation's attempted removal of her followers' brainwashing by having her top lieutenant and former "Ultimate Hope" Izuru Kamukura download her into their rehabilitation program "Neo World", where she places their younger virtual selves into another "killing game". In the game's climax, Junko's true plan is revealed to be to transfer her A.I self into the bodies of those of her followers whose virtual selves killed each other, their real selves (with whom she shared a polyamorous relationship) having arranged their capture to allow Junko a chance to return in a physical body, and from there to the watching Future Foundation and the wider world at large, to be dubbed "Junkoland". Ultimately, after her followers' virtual selves decide to remain in the program, Alter Ego Junko is deleted by a new manifestation of the program's former operator, Usami.

In the climax of Danganronpa Another Episode: Ultra Despair Girls, set between the first and second games, the Monokuma variants Shirokuma and Kurokuma are both revealed to be under the control of Alter Ego Junko, with the goal of molding Monaca Towa to become the "heir to despair", before they are both destroyed by Izuru Kamukura so he can transfer her to a USB to bring with him to Jabberwock Island, setting up the events of Danganronpa 2: Goodbye Despair.[7]

Junko appears in a cameo appearance in the third main series installment, Danganronpa V3: Killing Harmony, in the bonus minigame "Ultimate Talent Development Plan", with the game's new ultimate mastermind behind Monokuma being a copycat cosplay fan of Junko who seeks to continue her legacy, with the return of the true Junko being teased multiple times throughout the game.

In the "Despair Arc" of Danganronpa 3: The End of Hope's Peak High School, set before the events of the first game, Junko is collected from the airport by Mukuro in a limo after she blows up her taxi. While alluding to their incestuous relationship, the pair attempt to see if they can kill one another and experience the "Ultimate Despair", before Junko explains that the pair have been scouted to attend Hope's Peak Academy, Mukuro as the "Ultimate Soldier", and Junko as both the "Ultimate Fashionista" and "Ultimate Analyst". At their entrance ceremony, Junko sketches a picture of Monokuma. Two years later, Junko and Mukuro slaughter their way to confront and destroy Hope's Peak Academy's "Ultimate Hope" Izuru Kamukura, intending to kill him, only for the pair to be easily defeated. After sharing their love for despair with him and pitching that they join their cause, Izuru deduces the "Despair Sisters" are too bored with the world and share similar analytical abilities to himself, agreeing to join their cause, before knocking the pair out so that he may escape. Later, Junko and Mukuro recruit the "Ultimate Animator" Ryota Mitarai, whom they share as a lover, to develop a brainwashing anime to serve their cause, which they test on the "Ultimate Nurse" Mikan Tsumiki, who pledges herself to the sisters in the name of despair. Contacting Izuru once again, Junko and Mukuro arrange for their first "killing game" with the Academy's student council, trapping them on a floor of the school and providing blackmail on their elite parents' various scandals, with Izuru partaking in the event and killing the final survivor. Junko subsequently betrays Izuru by sending a mass e-mail to the students of the Reserve Course exposing his existence along with the footage of her killing game and how their funding had been used for human experimentation, leading to a mass riot and protest dubbed "The Parade".

After deciding to use her own class for her next killing game, Junko and Mukuro create a new brainwashing video they dub the "Despair Video" with the intent of sharing it with the entirety of the Reserve Course and pull in further support for "Ultimate Despair", drawing in Nagito Komaeda and a class representative who would later serve as the basis for Chiaki Nanami, investigating the cause of the first killing game, now dubbed "The Tragedy". However, after their homeroom teacher Chisa Yukizome comes across the group, creating a diversion by throwing a fire extinguisher, the pair escape, leaving Chisa to be brainwashed and lobotomised by Junko and Mukuro, after firstly demonstrating the loyalty of their followers by having a Reserve Course student commit suicide.

Later, Junko addresses the representative "Chiaki" via a monitor and traps her inside a test course for her "punishment" centre, intended to induce the rest of Nagito's class to her cause via brainwashing. Overlooking the city before the school from its roof, Junko, Mukuro and Izuru stand triumphant as they plan to "infect" the world with despair, before sending a mass text to the Reserve Course students, ordering them to commit mass suicide, to which Mukuro stares at Junko in admiration, loyalty and lust, glad to die for her cause if Junko would ever feel the need to kill them. Sending Izuru to lead her class in bringing despair to the world, Junko prepares for the coming apocalypse.

Several months later, shortly before the events of Danganronpa: Trigger Happy Havoc, Junko and Mukuro assist their class in converting the academy into a bunker to protect them from the chaos outside, while secretly preparing to have them detained to begin their killing game. After Makoto unknowingly displays his "ultimate luck", which Junko realises she cannot predict, she rejects Mukuro's suggestion that they kill him, believing that it would be more despair-inducing for her if someone as "ordinary" like Makoto was able to potentially defeat her, setting up her own end.[8]

In the "Future and Hope Arc" of Danganronpa 3: The End of Hope's Peak High School, set after the events of the second game, Junko makes a cameo appearance in the title sequence and in a flashback to her using blackmail to arrange to have her role in the fall of Hope's Peak Academy hidden from public knowledge. Later, Junko appears in the afterlife, talking with the spirit of Chisa while watching the events of her successor's "final killing game."[9][10]

Junko Enoshima appears in the Japanese manga adaptation of the series, written and illustrated by Touya Hajime and published by Enterbrain, as well as the spin-off Killer Killer. The series was published in the United States by Enterbrain USA. An additional manga series, published by Ichijinsha, was released solely in Japan.[11][12][13] Junko is also the main protagonist of the light novel series Danganronpa/Zero.[14][15] A Japanese musical and series of stage plays based on the series, sponsored by Kellogg's Cornflakes, cast actor Sayaka Kanda as Junko Enoshima, in addition to confirming her incestuous relationship with her sister Mukuro Ikusaba (whom Kanda also portrays) formerly only inferred in previous media, adapting the events of the first two games and the anime series and featuring Nobuyo Ōyama and TARAKO reprising their roles as Monokuma from the video game series.[16][17][18][19][20][21]

Junko is depicted in the 2019 Spike Chunsoft game AI: The Somnium Files, in which protagonists Date and his A.I. Aiba discover an autograph left by Junko in the titular somnium, featuring a drawing of herself with two Monokuma robots. The game is additionally implied to be set in the same fictional universe as Danganronpa in the resulting conversation between the duo.

Junko is included as a playable character in a 2020 crossover event of the NetEase horror game, Identity V, alongside her Monokuma form and fellow Danganronpa characters Makoto Naegi and Kyoko Kirigiri, where she (in either form) pursues the latter pair with a hammer, with the intent of executing them.[22]