Letitia Christian Tyler

They married on Tyler's 23rd birthday at Cedar Grove, her family's home. Their 29-year marriage appears to have been a happy one. Letitia Tyler avoided the limelight during her husband's political rise, preferring domestic responsibilities to those of a public wife. During his congressional service, she remained in Virginia except for one visit to Washington during the winter of 1828–1829. In 1839, she suffered a paralytic stroke that left her an invalid. As first lady, she remained in the upstairs living quarters of the White House; she came down once, to attend the wedding of her daughter (Elizabeth) in January 1842.[6]

Together, John and Letitia Tyler had four daughters and three sons live to maturity:[7]

• Mary Tyler-Jones (1815–1848), who married Henry Lightfoot Jones, a prosperous Tidewater planter, in 1835.
• Robert Tyler (1816–1877), who was a lawyer, public official who served as his father's private secretary in the White House. He settled in Philadelphia, where he practiced law and served as sheriff's solicitor. He also was chief clerk of the state supreme court. He married Priscilla Cooper Tyler, an actress, who at the age of 24 assumed the position of White House hostess, and she served as official hostess at the White House during the first three years of the Tyler administration. As a leader of the Democratic Party in Pennsylvania, Robert Tyler promoted the career of James Buchanan. At the outbreak of the American Civil War, he fled Philadelphia when an anti-southern mob attacked his home. He returned to Virginia, where he served as register of the Treasury of the Confederacy. Penniless after the war, he settled in Montgomery, Alabama, and there regained his fortunes as a lawyer, editor of the Montgomery Advertiser, and leader of the state Democratic Party.
• John Tyler III (1819–1896), who was a lawyer, public official. Like his older brother, he also became a lawyer and served as private secretary to his father, campaigning for James Buchanan. During the Civil War, he served as assistant secretary of war of the Confederacy. After the war, he settled in Baltimore, where he practiced law. Under the Grant administration, he was appointed to a minor position in the IRS in Tallahassee, FL.
• Letitia Tyler-Semple (1821–1907), an educator married James Semple, whom her father appointed a purser in the U.S. Navy, in 1839. The marriage was an unhappy one. At the close of the American Civil War, she left her husband to open a school, the Eclectic Institute, in Baltimore. After her mother's death in 1842, and after her sister-in-law Priscilla moved away, Letitia served her father as the White House social hostess, the title later known as First Lady. Her father remarried in 1844.
• Elizabeth Tyler-Waller (1823–1850), who married William N. Waller at a White House wedding in 1842. She died from the effects of childbirth at the age of 27.
• Alice Tyler-Denison (1827–1854), who married the Reverend Henry M. Denison, an Episcopal rector in Williamsburg, in 1850. She died suddenly of colic, also at the age of 27.
• Tazewell Tyler (1830–1874), who was a doctor who served as a surgeon in the Confederate Army during the Civil War.