List of highways numbered 16

• Asian Highway 16
• E16 European route E16
• E016 European route E016

 - Thompsons Road (Victoria)   

 - South Australia

Parts of the Trans-Canada Highway

• Yellowhead Highway, part of the Trans-Canada Highway system
  • Alberta Highway 16
    • Alberta Highway 16A
    • Alberta Highway 16X (former)
  • British Columbia Highway 16
  • Manitoba Highway 16
    • Manitoba Highway 16A
  • Saskatchewan Highway 16
    • Saskatchewan Highway 16A
    • Saskatchewan Highway 16B

• New Brunswick Route 16

Other instances of Highway 16

• Nova Scotia Trunk 16
• Ontario Highway 16
• Prince Edward Island Route 16

• G16 Expressway

• I/16 Highway; Czech: Silnice I/16

16

National Highway 16 (India)

• Highway 16 (Israel)

• Road 16

• Japan National Route 16
• Route 16 (Nagoya Expressway)
• Ōsakakō Route

• Ulsan Expressway

• New Zealand State Highway 16

• British A16 (Peterborough-Grimsby)

• Interstate 16
• U.S. Route 16
• New England Route 16 (former)
• Alabama State Route 16 (former)
• Arkansas Highway 16
• California State Route 16
  • County Route A16 (California)
  • County Route E16 (California)
  • County Route G16 (California)
  • County Route J16 (California)
  • County Route S16 (California)
• Colorado State Highway 16
• Connecticut Route 16
• Delaware Route 16
• Florida State Road 16
• Georgia State Route 16
• Hawaii Route 16 (former)
• Idaho State Highway 16
• Illinois Route 16
• Indiana State Road 16
• Iowa Highway 16
• K-16 (Kansas highway)
• Kentucky Route 16
• Louisiana Highway 16
  • Louisiana State Route 16 (former)
• Maine State Route 16
• Maryland Route 16
• Massachusetts Route 16
• M-16 (Michigan highway) (former)
• Minnesota State Highway 16
  • County Road 16 (St. Louis County, Minnesota)
• Mississippi Highway 16
• Missouri Route 16
• Montana Highway 16
• Nebraska Highway 16
  • Nebraska Spur 16B
  • Nebraska Spur 16F
  • Nebraska Recreation Road 16C
  • Nebraska Recreation Road 16D
• Nevada State Route 16 (former)
• New Hampshire Route 16
  • New Hampshire Route 16B
• New Mexico State Road 16
• County Route 16 (Monmouth County, New Jersey)
• New York State Route 16
  • County Route 16 (Allegany County, New York)
  • County Route 16 (Cattaraugus County, New York)
  • County Route 16 (Cayuga County, New York)
  • County Route 16 (Chautauqua County, New York)
  • County Route 16 (Chenango County, New York)
  • County Route 16 (Clinton County, New York)
  • County Route 16 (Dutchess County, New York)
  • County Route 16 (Franklin County, New York)
  • County Route 16 (Herkimer County, New York)
  • County Route 16 (Lewis County, New York)
  • County Route 16 (Monroe County, New York)
  • County Route 16 (Oneida County, New York)
  • County Route 16 (Orange County, New York)
  • County Route 16 (Otsego County, New York)
  • County Route 16 (Putnam County, New York)
  • County Route 16 (Rensselaer County, New York)
  • County Route 16 (Schenectady County, New York)
  • County Route 16 (Schuyler County, New York)
  • County Route 16 (Steuben County, New York)
  • County Route 16 (Suffolk County, New York)
  • County Route 16 (Ulster County, New York)
  • County Route 16 (Warren County, New York)
• North Carolina Highway 16
• North Dakota Highway 16
• Ohio State Route 16
• Oklahoma State Highway 16
• Pennsylvania Route 16
• South Carolina Highway 16
• South Dakota Highway 16 (former)
  • South Dakota Highway 16B (former)
• Tennessee State Route 16
• Texas State Highway 16
  • Texas State Highway Loop 16 (former)
  • Texas State Highway Spur 16
  • Farm to Market Road 16
  • Texas Park Road 16
• Utah State Route 16
• Vermont Route 16
• Virginia State Route 16
  • State Route 16 (Virginia 1918-1940) (former)
• Washington State Route 16
  • Primary State Highway 16 (Washington) (former)
• West Virginia Route 16
• Wisconsin Highway 16

Territories

• Guam Highway 16
• Puerto Rico Highway 16

• List of A16 roads
• List of highways numbered 16A
• Route-16