Methyl hydroxychalcone
Methyl hydroxychalcone is a chalconoid found in cinnamon. It was thought to be an insulin mimetic, improving insulin response of diabetics.[1] It has since been determined that a flavonoid (cinnamtannin B1) is responsible for the insulin-like biological activity.[2]
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| Names | |
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| IUPAC name
(E)-3-(3-hydroxyphenyl)-1-(3-methylphenyl)prop-2-en-1-one | |
| Other names
MCHP 3'-Methyl-3-hydroxychalcone | |
| Identifiers | |
3D model (JSmol) |
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| Properties | |
| C16H14O2 | |
| Molar mass | 238.28 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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See also
References
- Karalee J. Jarvill-Taylor, PhD; Richard A. Anderson, PhD; Donald J. Graves, PhD (August 1, 2001). "A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes". J Am Coll Nutr. 20 (4): 327–36. doi:10.1080/07315724.2001.10719053. PMID 11506060. S2CID 34049517. Archived from the original on 2004-08-11. Retrieved 2014-02-27.
- Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014.
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