PP cell
Pancreatic polypeptide cells (PP cells), or formerly as gamma cells, or F cells, are cells in the pancreatic islets (Islets of Langerhans) of the pancreas. The produce pancreatic polypeptide, after which they are named. They are very few in number and are polygonal in shape.
| PP cell | |
|---|---|
 PP cells (red), alpha cells (white) and beta cells (green) in PP cell rich area of Pancreatic Islet. | |
| Details | |
| Location | Islets of Langerhans of pancreas |
| Function | Pancreatic polypeptide production |
| Identifiers | |
| TH | H3.04.02.0.00035 |
| Anatomical terms of microanatomy | |
Structure
PP cells tend to located in the pancreatic islets, and are one of the rarer pancreatic cell types.[1] Some small clusters may also be found surrounded by exocrine pancreas.[2] They tend to be located in the duodenal part of the pancreas more medially.[2] They are polygonal in shape.[1]
PP cells have few granules.[3] They also have very few organelles.
Other animals
In cats and dogs, PP cells have large granules.[3] In rats, PP cells have few granules, similar to humans.
In dogs, some PP cells are located in the walls of the antrum of the stomach.[2]
References
- Kerr, Jeffrey B. (2000). Atlas of functional histology. London: Harcourt Publishers. ISBN 0-7234-3072-1. OCLC 40347416.
- Kono, Tetsuya; Wang, Xiao-Ping; Fisher, William E.; Andersen, Dana K.; Brunicardi, F. Charles (2004-01-01), Martini, Luciano (ed.), "Pancreatic Polypeptide (PP)", Encyclopedia of Endocrine Diseases, New York: Elsevier, pp. 488–496, doi:10.1016/b0-12-475570-4/01055-6, ISBN 978-0-12-475570-3, retrieved 2021-02-03
- Larsson, Lars-Inge (2004-01-01), Martini, Luciano (ed.), "GI Hormones and Endocrine Pancreas: Expressional Regulation", Encyclopedia of Endocrine Diseases, New York: Elsevier, pp. 173–176, ISBN 978-0-12-475570-3, retrieved 2021-02-03
